Complete Clinical Response after Chemoradiotherapy in Rectal Cancer: A Crossroad
نویسندگان
چکیده
منابع مشابه
Predictors of pathologic complete response after preoperative concurrent chemoradiotherapy of rectal cancer: a single center experience
PURPOSE To identify possible predictors of pathologic complete response (pCR) of rectal cancer after preoperative concurrent chemoradiotherapy (CCRT). MATERIALS AND METHODS We conducted a retrospective review of 53 patients with rectal cancer who underwent preoperative CCRT followed by radical surgery at a single center between January 2007 and December 2012. The median radiotherapy dose to t...
متن کاملClinical parameters predicting pathologic complete response following neoadjuvant chemoradiotherapy for rectal cancer.
INTRODUCTION Preoperative chemoradiotherapy (CRT), followed by total mesorectal excision, has become the standard of care for patients with clinical stages II and III rectal cancer. Patients with pathologic complete response (pCR) to preoperative CRT have been reported to have better outcomes than those without pCR. However, the factors that predict the response to neoadjuvant CRT have not been...
متن کاملChemoradiotherapy response in recurrent rectal cancer
The efficacy of response to preoperative chemoradiotherapy (CRT) in recurrent versus primary rectal cancer has not been investigated. We compared radiological downsizing between primary and recurrent rectal cancers following CRT and determined the optimal size reduction threshold for response validated by survival outcomes. The proportional change in tumor length for primary and recurrent recta...
متن کاملComplete pathologic response after chemoradiotherapy in a patient with rectal squamous cell carcinoma: a case report
Squamous cell carcinoma (SCC) of the rectum is a rare disease. A 59-year-old man presented with SCC of the middle rectum located 10 cm from the anus. The stage of the tumor was revealed to be T3N+M0. The patient received a combined treatment with cisplatin and fluorouracil in concomitance with external radiation therapy. He then underwent an anterior resection of the rectum. The postoperative h...
متن کاملClinical predictive factors of pathologic tumor response after preoperative chemoradiotherapy in rectal cancer
PURPOSE The aim of this study was to identify clinical predictive factors for tumor response after preoperative chemoradiotherapy (CRT) in rectal cancer. MATERIALS AND METHODS The study involved 51 patients who underwent preoperative CRT followed by surgery between January 2005 and February 2012. Radiotherapy was delivered to the whole pelvis at a dose of 45 Gy in 25 fractions, followed by a ...
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ژورنال
عنوان ژورنال: Journal of the American College of Surgeons
سال: 2020
ISSN: 1072-7515
DOI: 10.1016/j.jamcollsurg.2020.07.082